Concentration of amino acids (Phe, Tyr, Cys, Arg)

Amino acid

Peptide fractions

Control

Tumour

Amino acid

Peptide fractions

Control

Tumour

Phe

[μg/mg protein]

6.2 8.2 9.1 11.7 12.6 14.0 17.1 27.4 28.9 30.7

2.61 ± 0.53 1.34 ± 0.15 1.65 ± 0.22 2.43 ± 0.14 2.73 ± 0.17 1.69 ± 0.34 1.71 ± 0.33 1.58 ± 0.14 2.85 ± 0.56 3.04 ± 0.11

1.97 ± 0.49 1.01 ± 0.15^x

1.18 ± 0.12^x

1.58 ± 0.10^x

2.15 ± 0.10^x

1.22 ± 0.14 1.16 ± 0.22 1.02 ± 0.08^x

1.83 ± 0.37^x

2.02 ± 0.13^x

Tyr

[ng/mg protein]

6.2 8.2 9.1 11.7 12.6 14.0 17.1 27.4 28.9 30.7

0.26 ± 0.03 0.30 ± 0.04 0.21 ± 0.01 0.24 ± 0.05 0.30 ± 0.02 0.18 ± 0.03 0.28 ± 0.05 0.29 ± 0.03 0.19 ± 0.06 0.30 ± 0.02

0.18 ± 0.02^x

0.21 ± 0.03^x

0.13 ± 0.07 0.18 ± 0.04 0.21 ± 0.02^x

0.10 ± 0.02 0.24 ± 0.04 0.19 ± 0.03^x

0.14 ± 0.05 0.21 ± 0.01^x

Cys

[ng/mg protein]

6.2 8.2 9.1 11.7 12.6 14.0 17.1 27.4 28.9 30.7

40.3 ± 9.38 60.2 ± 5.12 42.0 ± 2.31 36.2 ± 2.81 33.0 ± 6.07 27.4 ± 4.96 37.5 ± 2.68 30.2 ± 2.37 28.4 ± 3.54 36.0 ± 5.11

31.8 ± 7.21 50.7 ± 3.30^x

26.2 ± 1.99^x

22.4 ± 2.50^x

25.5 ± 5.34 22.9 ± 4.01 23.4 ± 4.11^x

21.6 ± 2.29^x

20.5 ± 3.09^x

26.6 ± 4.12^x

Arg

[μg/mg protein]

6.2 8.2 9.1 11.7 12.6 14.0 17.1 27.4 28.9 30.7

9.10 ± 0.52 8.22 ± 1.09 5.88 ± 1.49 3.95 ± 0.44 4.96 ± 0.55 9.51 ± 1.05 4.17 ± 0.48 7.12 ± 0.66 4.03 ± 0.61 4.17 ± 0.65

6.72 ± 0.21^x

5.92 ± 0.93^x

3.67 ± 1.26 2.45 ± 0.40^x

3.24 ± 0.35 7.44 ± 1.08 2.70 ± 0.40^x

5.43 ± 0.55^x

2.09 ± 0.30^x

2.61 ± 0.44^x